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| PDOC00744 |
Ribosomal protein S2 signatures
Description:
Ribosomal protein S2 is one of the proteins from the small ribosomal subunit.
S2 belongs to a family of ribosomal proteins which, on the basis of sequence
similarities [1,2], groups:
- Eubacterial S2.
- Algal and plant chloroplast S2.
- Cyanelle S2.
- Archaebacterial S2.
- Higher eukaryotes P40 (previously thought to be a laminin receptor).
- Yeast NAB1.
- Plant mitochondrial S2.
- Yeast mitochondrial MRP4.
S2 is a protein of 235 to 394 amino-acid residues. As signature patterns, we
selected two conserved regions. One is located in the N-terminal section and
the other in the central section.
Last update:
December 2004 / Pattern and text revised.
Technical section:
PROSITE methods (with tools and information) covered by this documentation:
| RIBOSOMAL_S2_1, PS00962; Ribosomal protein S2 signature 1 (PATTERN) |
| Consensus pattern: |
[LIVMFA] - x - {GPRV} - [LIVMFYC](2) - {LPC} - [STAC] - [GSTANQEKR] - [STALV] - [HY] - [LIVMF] - G
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| Sequences known to belong to this class detected by the pattern: |
ALL, except for three sequences |
| Other sequence(s) detected in Swiss-Prot: |
41. |
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| Matching PDB structures:
1FJG 1GIX 1HNW 1HNX ... [ALL] |
| RIBOSOMAL_S2_2, PS00963; Ribosomal protein S2 signature 2 (PATTERN) |
| Consensus pattern: |
P - x(2) - [LIVMF](2) - [LIVMS] - x - [GDN] - x(3) - [DENL] - x(3) - [LIVM] - x - E - x(4) - [GNQKRH] - [LIVM] - [AP]
|
| Sequences known to belong to this class detected by the pattern: |
ALL |
| Other sequence(s) detected in Swiss-Prot: |
NONE. |
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|
| Matching PDB structures:
1K5X 1M5G 1P87 1S1H ... [ALL] |
References:
| 1 |
Authors | Davis S.C., Tzagoloff A., Ellis S.R. |
| Title | Characterization of a yeast mitochondrial ribosomal protein structurally related to the mammalian 68-kDa high affinity laminin receptor. |
| Source | J. Biol. Chem. 267:5508-5514(1992). |
| PubMed ID | 1531984 |
| 2 |
Authors | Tohgo A., Takasawa S., Munakata H., Yonekura H., Hayashi N., Okamoto H. |
| Title | Structural determination and characterization of a 40 kDa protein isolated from rat 40 S ribosomal subunit. |
| Source | FEBS Lett. 340:133-138(1994). |
| PubMed ID | 8119397 |
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