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PDOC00744

Ribosomal protein S2 signatures

Description:

Ribosomal protein S2 is one of the proteins from the small ribosomal subunit. S2 belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:

  • Eubacterial S2.
  • Algal and plant chloroplast S2.
  • Cyanelle S2.
  • Archaebacterial S2.
  • Higher eukaryotes P40 (previously thought to be a laminin receptor).
  • Yeast NAB1.
  • Plant mitochondrial S2.
  • Yeast mitochondrial MRP4.

S2 is a protein of 235 to 394 amino-acid residues. As signature patterns, we selected two conserved regions. One is located in the N-terminal section and the other in the central section.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE methods (with tools and information) covered by this documentation:

RIBOSOMAL_S2_1, PS00962Ribosomal protein S2 signature 1  (PATTERN)
Consensus pattern: [LIVMFA] - x - {GPRV} - [LIVMFYC](2) - {LPC} - [STAC] - [GSTANQEKR] - [STALV] - [HY] - [LIVMF] - G
Sequences known to belong to this class detected by the pattern: ALL, except for three sequences
Other sequence(s) detected in Swiss-Prot: 41.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00962
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00962
Scan Swiss-Prot/TrEMBL entries against PS00962
view ligand binding statistics
Matching PDB structures: 1FJG 1GIX 1HNW 1HNX ... [ALL]
RIBOSOMAL_S2_2, PS00963Ribosomal protein S2 signature 2  (PATTERN)
Consensus pattern: P - x(2) - [LIVMF](2) - [LIVMS] - x - [GDN] - x(3) - [DENL] - x(3) - [LIVM] - x - E - x(4) - [GNQKRH] - [LIVM] - [AP]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00963
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00963
Scan Swiss-Prot/TrEMBL entries against PS00963
view ligand binding statistics
Matching PDB structures: 1K5X 1M5G 1P87 1S1H ... [ALL]

References:

1 AuthorsDavis S.C., Tzagoloff A., Ellis S.R.
TitleCharacterization of a yeast mitochondrial ribosomal protein structurally related to the mammalian 68-kDa high affinity laminin receptor.
SourceJ. Biol. Chem. 267:5508-5514(1992).
PubMed ID1531984
2 AuthorsTohgo A., Takasawa S., Munakata H., Yonekura H., Hayashi N., Okamoto H.
TitleStructural determination and characterization of a 40 kDa protein isolated from rat 40 S ribosomal subunit.
SourceFEBS Lett. 340:133-138(1994).
PubMed ID8119397

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