ID   6.3.2.26
DE   N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase.
AN   ACV synthetase.
AN   L-alpha-aminoadipyl-cysteinyl-valine synthetase.
AN   L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase.
CA   L-2-aminohexanedioate + L-cysteine + L-valine + 3 ATP + H(2)O = N-(L-5-
CA   amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate.
CF   Magnesium.
CC   -!- The enzyme contains 4'-phosphopantetheine, which may be involved in
CC       the mechanism of the reaction.
CC   -!- Forms part of the penicillin biosynthesis pathway.
PR   PROSITE; PDOC00427;
DR   P19787, ACVS1_PENCH;  P26046, ACVS2_PENCH;  P25464, ACVS_CEPAC ;
DR   P27742, ACVS_EMENI ;  P27743, ACVS_NOCLA ;  Q01757, ACVS_STRCL ;
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