| Official Name |
|---|
| Lysine--tRNA(Pyl) ligase.
|
| Reaction catalysed |
|---|
| ATP + L-lysine + tRNA(Pyl) <=> AMP + diphosphate + L-lysyl-tRNA(Pyl) |
| Comment(s) |
|---|
- In organisms such as Methanosarcina barkeri that incorporate the
modified amino acid pyrrolysine (Pyl) into certain methylamine
methyltransferases, an unusual tRNA(Pyl), with a CUA anticodon,
is charged directly with pyrrolysine by this class II aminoacyl--tRNA
ligase.
- The tRNA and the ligase are encoded within the same gene cluster,
and the ligase does not appear to be closely related to EC 6.1.1.6.
|
| Cross-references |
|---|
| BRENDA | 6.1.1.25 |
| PUMA2 | 6.1.1.25 |
| PRIAM enzyme-specific profiles | 6.1.1.25 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.1.1.25 |
| IUBMB Enzyme Nomenclature | 6.1.1.25 |
| IntEnz | 6.1.1.25 |
| MEDLINE | Find literature relating to 6.1.1.25 |
| MetaCyc | 6.1.1.25 |
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