| Official Name |
|---|
| DNA topoisomerase (ATP-hydrolyzing).
|
| Alternative Name(s) |
|---|
| DNA gyrase. |
| DNA topoisomerase II. |
| Type II DNA topoisomerase. |
| Reaction catalysed |
|---|
| ATP-dependent breakage, passage and rejoining of double-stranded DNA |
| Comment(s) |
|---|
- Can introduce negative superhelical turns into double-stranded
circular DNA.
- One unit has nicking-closing activity, and another catalyzes super-
twisting and hydrolysis of ATP (cf. EC 5.99.1.2).
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | N7 ; N8 ; S7 ; S8 |
| PROSITE | PDOC00160 |
| BRENDA | 5.99.1.3 |
| PUMA2 | 5.99.1.3 |
| PRIAM enzyme-specific profiles | 5.99.1.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.99.1.3 |
| IUBMB Enzyme Nomenclature | 5.99.1.3 |
| IntEnz | 5.99.1.3 |
| MEDLINE | Find literature relating to 5.99.1.3 |
| MetaCyc | 5.99.1.3 |
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