ENZYME entry: EC 5.6.2.3
Accepted Name | |||||||||||||||||||
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DNA 5'-3' helicase | |||||||||||||||||||
Alternative Name(s) | |||||||||||||||||||
5' to 3' DNA helicase | |||||||||||||||||||
replication fork helicase | |||||||||||||||||||
replicative DNA helicase | |||||||||||||||||||
Reaction catalysed | |||||||||||||||||||
Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction. This creates two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is the template for DNA polymerase III holoenzyme which synthesizes a continuous strand | |||||||||||||||||||
Comment(s) | |||||||||||||||||||
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Cross-references | |||||||||||||||||||
BRENDA | 5.6.2.3 | ||||||||||||||||||
EC2PDB | 5.6.2.3 | ||||||||||||||||||
ExplorEnz | 5.6.2.3 | ||||||||||||||||||
PRIAM enzyme-specific profiles | 5.6.2.3 | ||||||||||||||||||
KEGG Ligand Database for Enzyme Nomenclature | 5.6.2.3 | ||||||||||||||||||
IUBMB Enzyme Nomenclature | 5.6.2.3 | ||||||||||||||||||
IntEnz | 5.6.2.3 | ||||||||||||||||||
MEDLINE | Find literature relating to 5.6.2.3 | ||||||||||||||||||
MetaCyc | 5.6.2.3 | ||||||||||||||||||
Rhea expert-curated reactions | 5.6.2.3 | ||||||||||||||||||
UniProtKB/Swiss-Prot |
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