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NiceZyme View of ENZYME: EC 5.4.99.18

Official Name
5-(carboxyamino)imidazole ribonucleotide mutase.
Alternative Name(s)
N(5)-CAIR mutase.
N(5)-carboxyaminoimidazole ribonucleotide mutase.
Reaction catalysed
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
Comment(s)
  • In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.
  • In the absence of EC 6.3.2.6, the reaction is reversible.
  • The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation.
Cross-references
BRENDA5.4.99.18
PUMA25.4.99.18
PRIAM enzyme-specific profiles5.4.99.18
KEGG Ligand Database for Enzyme Nomenclature5.4.99.18
IUBMB Enzyme Nomenclature5.4.99.18
IntEnz5.4.99.18
MEDLINEFind literature relating to 5.4.99.18
MetaCyc5.4.99.18

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