| Accepted Name |
|---|
| Bisphosphoglycerate mutase.
|
| Alternative Name(s) |
|---|
| 2,3-bisphosphoglycerate mutase. |
| 2,3-bisphosphoglycerate synthase. |
| 2,3-diphosphoglycerate mutase. |
| Bisphosphoglycerate synthase. |
| BPGM. |
| Diphosphoglycerate mutase. |
| Diphosphoglyceromutase. |
| Glycerate phosphomutase. |
| Reaction catalysed |
|---|
| 3-phospho-D-glyceroyl phosphate <=> 2,3-bisphospho-D-glycerate |
| Comment(s) |
|---|
- In the direction shown, the enzyme is phosphorylated by
3-phosphoglyceroyl phosphate to give phosphoenzyme and
3-phosphoglycerate.
- The latter is rephosphorylated by the enzyme to yield 2,3-
diphosphoglycerate, but this reaction is slowed down by dissociation
of 3-phosphoglycerate from the enzyme, which is therefore more active
in the presence of added 3-phosphoglycerate.
- Also catalyzes, slowly, the reactions of EC 3.1.3.13 and EC 5.4.2.1.
- Formerly EC 2.7.5.4.
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | D5 |
| PROSITE | PDOC00158 |
| BRENDA | 5.4.2.4 |
| EC2PDB | 5.4.2.4 |
| PRIAM enzyme-specific profiles | 5.4.2.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.4.2.4 |
| IUBMB Enzyme Nomenclature | 5.4.2.4 |
| IntEnz | 5.4.2.4 |
| MEDLINE | Find literature relating to 5.4.2.4 |
| MetaCyc | 5.4.2.4 |
| UniProtKB/Swiss-Prot |
| Q3SZ62, PGAM1_BOVIN; | Q5ZLN1, PGAM1_CHICK; | P18669, PGAM1_HUMAN; |
| Q9DBJ1, PGAM1_MOUSE; | Q5RFB8, PGAM1_PONAB; | P25113, PGAM1_RAT; |
| Q32KV0, PGAM2_BOVIN; | P15259, PGAM2_HUMAN; | O70250, PGAM2_MOUSE; |
| P16290, PGAM2_RAT; | Q8N0Y7, PGAM4_HUMAN; | Q8MKE8, PGAM4_PANTR; |
| Q54NE6, PGAM_DICDI; | Q3T014, PMGE_BOVIN; | P07738, PMGE_HUMAN; |
| Q4R6L7, PMGE_MACFA; | P15327, PMGE_MOUSE; | P07952, PMGE_RABIT; |
|
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