| Official Name |
|---|
| Serine racemase.
|
| Reaction catalysed |
|---|
| L-serine <=> D-serine |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- Highly selective for L-serine as substrate.
- D-serine is found in type-II astrocytes in mammalian brain, where it
appears to be an endogenous ligand of the glycine site of N-methyl-D-
aspartate (NMDA) receptors.
- The reaction can also occur in the reverse direction but does so more
slowly at physiological serine concentrations.
|
| Cross-references |
|---|
| BRENDA | 5.1.1.18 |
| PUMA2 | 5.1.1.18 |
| PRIAM enzyme-specific profiles | 5.1.1.18 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.1.1.18 |
| IUBMB Enzyme Nomenclature | 5.1.1.18 |
| IntEnz | 5.1.1.18 |
| MEDLINE | Find literature relating to 5.1.1.18 |
| MetaCyc | 5.1.1.18 |
| UniProtKB/Swiss-Prot |
|
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