| Accepted Name |
|---|
| Cystathionine beta-lyase.
|
| Alternative Name(s) |
|---|
| Beta C-S lyase. |
| Beta-cystathionase. |
| Cysteine lyase. |
| Cystine lyase. |
| Reaction catalysed |
|---|
| L-cystathionine + H(2)O <=> L-homocysteine + NH(3) + pyruvate |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- The enzyme from some sources also acts on L-cystine, forming
pyruvate, ammonia and cysteine persulfide, and a number of related
compounds.
- Possibly identical, in Saccharomyces cerevisiae, with EC 4.4.1.6.
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | G4 ; I4 |
| PROSITE | PDOC00518 ; PDOC00677 |
| BRENDA | 4.4.1.8 |
| EC2PDB | 4.4.1.8 |
| PRIAM enzyme-specific profiles | 4.4.1.8 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.4.1.8 |
| IUBMB Enzyme Nomenclature | 4.4.1.8 |
| IntEnz | 4.4.1.8 |
| MEDLINE | Find literature relating to 4.4.1.8 |
| MetaCyc | 4.4.1.8 |
| UniProtKB/Swiss-Prot |
| Q08432, CBL_BACSU; | P63503, CBL_MYCBO; | Q9CBM9, CBL_MYCLE; |
| P63502, CBL_MYCTU; | O94350, CBL_SCHPO; | P23256, MALY_ECOLI; |
| P53780, METC_ARATH; | O31632, METC_BACSU; | Q07703, METC_BORAV; |
| Q83A83, METC_COXBU; | P85217, METC_CRYLA; | P06721, METC_ECOLI; |
| P44527, METC_HAEIN; | P0A4K2, METC_LACLA; | P0C2T9, METC_LACLC; |
| A2RM21, METC_LACLM; | Q52811, METC_RHIL3; | P18949, METC_SALTY; |
| P43623, METC_YEAST; | P53101, STR3_YEAST; |
|
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