| Official Name |
|---|
| L-serine ammonia-lyase.
|
| Alternative Name(s) |
|---|
| L-hydroxyaminoacid dehydratase. |
| L-serine deaminase. |
| L-serine dehydratase. |
| L-serine hydro-lyase (deaminating). |
| Serine deaminase. |
| Reaction catalysed |
|---|
| L-serine <=> pyruvate + NH(3) |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- This reaction is also carried out by EC 4.3.1.19 from a number of
sources.
- The reaction catalyzed probably involves initial elimination of water
(hence the enzyme's original classification as EC 4.2.1.13), followed
by isomerization and hydrolysis of the product with C-N bond
breakage.
- Formerly EC 4.2.1.13.
|
| Cross-references |
|---|
| PROSITE | PDOC00149 |
| BRENDA | 4.3.1.17 |
| PUMA2 | 4.3.1.17 |
| PRIAM enzyme-specific profiles | 4.3.1.17 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.3.1.17 |
| IUBMB Enzyme Nomenclature | 4.3.1.17 |
| IntEnz | 4.3.1.17 |
| MEDLINE | Find literature relating to 4.3.1.17 |
| MetaCyc | 4.3.1.17 |
| UniProtKB/Swiss-Prot |
| O34607, SDHA_BACSU; | P80212, SDHA_CLOPR; | Q48838, SDHA_LACSK; |
| P33073, SDHA_PEPAS; | O34635, SDHB_BACSU; | P80213, SDHB_CLOPR; |
| P33074, SDHB_PEPAS; | Q0VCW4, SDHL_BOVIN; | Q86B06, SDHL_DICDI; |
| P16095, SDHL_ECOLI; | P71349, SDHL_HAEIN; | Q9ZMU7, SDHL_HELPJ; |
| P56072, SDHL_HELPY; | P20132, SDHL_HUMAN; | Q8VBT2, SDHL_MOUSE; |
| P66774, SDHL_MYCBO; | P66773, SDHL_MYCTU; | P09367, SDHL_RAT; |
| O86564, SDHL_STRCO; | P17324, SDHL_YEAST; | P30744, SDHM_ECOLI; |
| P25379, STDH_YEAST; | P42630, TDCG_ECOLI; |
|
ExPASy Home page