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NiceZyme View of ENZYME: EC 4.1.2.37

Official Name
Hydroxynitrilase.
Alternative Name(s)
2-hydroxyisobutyronitrile acetone-lyase.
Acetone-cyanohydrin acetone-lyase.
Acetone-cyanohydrin lyase.
Alpha-hydroxynitrile lyase.
Hydroxynitrile lyase.
Oxynitrilase.
Reaction catalysed
Acetone cyanohydrin <=> cyanide + acetone
Comment(s)
  • Accepts aliphatic and aromatic hydroxynitriles, unlike EC 4.1.2.11 which does not act on aliphatic hydroxynitriles.
  • 2-hydroxyisobutyronitrile (acetone cyanohydrin) is liberated by glycosidase action on linamarin.
  • Formerly EC 4.1.2.39.
Cross-references
BRENDA4.1.2.37
PUMA24.1.2.37
PRIAM enzyme-specific profiles4.1.2.37
KEGG Ligand Database for Enzyme Nomenclature4.1.2.37
IUBMB Enzyme Nomenclature4.1.2.37
IntEnz4.1.2.37
MEDLINEFind literature relating to 4.1.2.37
MetaCyc4.1.2.37
UniProtKB/Swiss-Prot
P52704, HNL_HEVBR;  P52705, HNL_MANES;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-

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