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ENZYME

ENZYME entry: EC 3.5.1.92

Accepted Name
pantetheine hydrolase
Alternative Name(s)
pantetheinase
vanin-1
Reaction catalysed
(R)-pantetheine + H2O <=> (R)-pantothenate + cysteamine
Comment(s)
  • Hydrolyzes only one of the amide bonds of pantetheine.
  • The substrate analogs phosphopantetheine and CoA are not substrates.
  • Recycles pantothenate (vitamin B5) and produces cysteamine, a potent anti-oxidant.
Cross-references
BRENDA3.5.1.92
EC2PDB3.5.1.92
ExplorEnz3.5.1.92
PRIAM enzyme-specific profiles3.5.1.92
KEGG Ligand Database for Enzyme Nomenclature3.5.1.92
IUBMB Enzyme Nomenclature3.5.1.92
IntEnz3.5.1.92
MEDLINEFind literature relating to 3.5.1.92
MetaCyc3.5.1.92
Rhea expert-curated reactions3.5.1.92
UniProtKB/Swiss-Prot
Q58CQ9, VNN1_BOVINQ9TSX8, VNN1_CANLFO95497, VNN1_HUMAN
Q9Z0K8, VNN1_MOUSEQ9BDJ5, VNN1_PIGO95498, VNN2_HUMAN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-