ID 3.4.24.47 DE Horrilysin. AN Crotalus horridus metalloendopeptidase. AN Hemorrhagic proteinase IV. CA Cleavage of only the single bond 14-Ala-|-Leu-15 in the insulin B chain, CA 12-Ser-|-Leu-13 in the A chain, and Ile-|-Gly, Pro-|-Ala, and Ser-|-Trp CA in mellitin. CF Zinc. CC -!- Cleaves basement membrane, hide powder and fibrinogen. CC -!- Hemorrhagic endopeptidase from the venom of the timber rattlesnake CC (Crotalus horridus horridus). CC -!- Belongs to peptidase family M12B. PR PROSITE; PDOC00129; //