ID   3.4.24.27
DE   Thermolysin.
AN   Bacillus thermoproteolyticus neutral proteinase.
CA   Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
CF   Calcium; Zinc.
CC   -!- A thermostable extracellular metalloendopeptidase containing four
CC       calcium ions.
CC   -!- Enzymes that may be species variants of thermolysin are reported from
CC       Micrococcus caseolyticus and Aspergillus oryzae.
CC   -!- Closely related but distinct enzymes are aeromonolysin, pseudolysin,
CC       bacillolysin, aureolysin and mycolysin.
CC   -!- Belongs to peptidase family M4.
PR   PROSITE; PDOC00129;
DR   Q43880, THER_ALIAC ;  Q59193, THER_BACCL ;  Q59223, THER_BACSO ;
DR   P06874, THER_BACST ;  P00800, THER_BACTH ;
//