| Official Name |
|---|
| Stromelysin 1.
|
| Alternative Name(s) |
|---|
| Matrix metalloproteinase 3. |
| Proteoglycanase. |
| Transin. |
| Reaction catalysed |
|---|
| Preferential cleavage where P1', P2' and P3' are hydrophobic residues |
| Cofactor(s) |
|---|
| Calcium; Zinc.
|
| Comment(s) |
|---|
- Extracellular endopeptidase of vertebrate tissues.
- Degradation of proteoglycans, fibronectin, collagen type III, IV,
V and IX and activates procollagenase.
- Belongs to peptidase family M10B.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.17 |
| PUMA2 | 3.4.24.17 |
| PRIAM enzyme-specific profiles | 3.4.24.17 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.17 |
| IUBMB Enzyme Nomenclature | 3.4.24.17 |
| IntEnz | 3.4.24.17 |
| MEDLINE | Find literature relating to 3.4.24.17 |
| MetaCyc | 3.4.24.17 |
| UniProtKB/Swiss-Prot |
|
ExPASy Home page