| Official Name |
|---|
| Procollagen N-endopeptidase.
|
| Alternative Name(s) |
|---|
| Procollagen N-proteinase. |
| Reaction catalysed |
|---|
| Cleaves the N-propeptide of collagen chain alpha-1(I) at Pro-|-Gln and of alpha-1(II) and alpha-2(I) at Ala-|-Gln |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Removes N-terminal propeptides of type I and II collagens prior to
fibril assembly.
- Does not cleave type III procollagen.
- Belongs to peptidase family M12.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.14 |
| PUMA2 | 3.4.24.14 |
| PRIAM enzyme-specific profiles | 3.4.24.14 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.14 |
| IUBMB Enzyme Nomenclature | 3.4.24.14 |
| IntEnz | 3.4.24.14 |
| MEDLINE | Find literature relating to 3.4.24.14 |
| MetaCyc | 3.4.24.14 |
| UniProtKB/Swiss-Prot |
|
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