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ENZYME

ENZYME entry: EC 3.4.23.50

Accepted Name
human endogenous retrovirus K endopeptidase
Alternative Name(s)
HERV K10 endopeptidase
HERV K10 retropepsin
human endogenous retrovirus K10 endopeptidase
human endogenous retrovirus K113 protease
human retrovirus K10 retropepsin
Reaction catalysed
Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site
Comment(s)
Belongs to peptidase family A2.
Cross-references
BRENDA3.4.23.50
EC2PDB3.4.23.50
ExplorEnz3.4.23.50
PRIAM enzyme-specific profiles3.4.23.50
KEGG Ligand Database for Enzyme Nomenclature3.4.23.50
IUBMB Enzyme Nomenclature3.4.23.50
IntEnz3.4.23.50
MEDLINEFind literature relating to 3.4.23.50
MetaCyc3.4.23.50
Rhea expert-curated reactions3.4.23.50
UniProtKB/Swiss-Prot
P63128, POK9_HUMANP63121, VP113_HUMANP63124, VPK04_HUMAN
P10265, VPK10_HUMANP63123, VPK18_HUMANP63120, VPK19_HUMAN
P63119, VPK21_HUMANP63129, VPK24_HUMANP63125, VPK25_HUMAN
Q9Y6I0, VPK6_HUMANP63131, VPK7_HUMANP63122, VPK8_HUMAN
P63127, VPK9_HUMAN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-