ENZYME entry: EC 3.4.23.45
Accepted Name | ||||
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memapsin 1 | ||||
Alternative Name(s) | ||||
ASP1 | ||||
BACE2 | ||||
beta-secretase | ||||
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 2 | ||||
beta-site APP-cleaving enzyme 2 | ||||
Down region aspartic protease | ||||
membrane-associated aspartic protease 1 | ||||
Reaction catalysed | ||||
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein | ||||
Comment(s) | ||||
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Cross-references | ||||
BRENDA | 3.4.23.45 | |||
EC2PDB | 3.4.23.45 | |||
ExplorEnz | 3.4.23.45 | |||
PRIAM enzyme-specific profiles | 3.4.23.45 | |||
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.45 | |||
IUBMB Enzyme Nomenclature | 3.4.23.45 | |||
IntEnz | 3.4.23.45 | |||
MEDLINE | Find literature relating to 3.4.23.45 | |||
MetaCyc | 3.4.23.45 | |||
Rhea expert-curated reactions | 3.4.23.45 | |||
UniProtKB/Swiss-Prot |
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