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NiceZyme View of ENZYME: EC 3.4.23.24

Accepted Name
Candidapepsin.
Alternative Name(s)
Candida albicans aspartic proteinase.
Reaction catalysed
Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 of insulin B chain. Activates trypsinogen, and degrades keratin
Comment(s)
  • This endopeptidase from the imperfect yeast Candida albicans is inhibited by pepstatin, but not by methyl 2-diazoacetamido-hexanoate or 1,2-epoxy-3-(p-nitrophenoxy)propane.
  • Belongs to peptidase family A1.
Cross-references
PROSITEPDOC00128
BRENDA3.4.23.24
EC2PDB3.4.23.24
PRIAM enzyme-specific profiles3.4.23.24
KEGG Ligand Database for Enzyme Nomenclature3.4.23.24
IUBMB Enzyme Nomenclature3.4.23.24
IntEnz3.4.23.24
MEDLINEFind literature relating to 3.4.23.24
MetaCyc3.4.23.24
UniProtKB/Swiss-Prot
P28872, CARP1_CANAL;  P32951, CARP1_CANPA;  P28871, CARP2_CANAL;  
P32950, CARP2_CANPA;  P43092, CARP3_CANAL;  P43093, CARP4_CANAL;  
P43094, CARP5_CANAL;  P43095, CARP6_CANAL;  P43096, CARP7_CANAL;  
O42778, CARP8_CANAL;  O42779, CARP9_CANAL;  Q00663, CARP_CANTR;  

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