| Official Name |
| Legumain.
|
| Alternative Name(s) |
| Asparaginyl endopeptidase. |
| Bean endopeptidase. |
| Hemoglobinase. |
| Phaseolin. |
| Vicilin peptidohydrolase. |
| Reaction catalysed |
| Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa-bonds |
| Comment(s) |
- Best known from legume seeds, the trematode Schistosoma mansoni and
mammalian lysosomes.
- Not inhibited by compound E-64.
- Belongs to peptidase family C13.
|
| Cross-references |
| PROSITE | PDOC00126 |
| BRENDA | 3.4.22.34 |
| PUMA2 | 3.4.22.34 |
| PRIAM enzyme-specific profiles | 3.4.22.34 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.22.34 |
| IUBMB Enzyme Nomenclature | 3.4.22.34 |
| IntEnz | 3.4.22.34 |
| MEDLINE | Find literature relating to 3.4.22.34 |
| MetaCyc | 3.4.22.34 |
| UniProtKB/Swiss-Prot |
| P80527, HGLB1_FASHE; | P80530, HGLB2_FASHE; | P42665, HGLB_SCHJA; |
| P09841, HGLB_SCHMA; | P49046, LEGU_CANEN; | Q95M12, LGMN_BOVIN; |
| Q99538, LGMN_HUMAN; | Q4R4T8, LGMN_MACFA; | O89017, LGMN_MOUSE; |
| Q5R5D9, LGMN_PONAB; | Q9R0J8, LGMN_RAT; |
|