| Official Name |
|---|
| Cathepsin B.
|
| Alternative Name(s) |
|---|
| Cathepsin B1. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides |
| Comment(s) |
|---|
- An intracellular (lysosomal) enzyme.
- Belongs to peptidase family C1.
|
| Cross-references |
|---|
| PROSITE | PDOC00126 |
| BRENDA | 3.4.22.1 |
| PUMA2 | 3.4.22.1 |
| PRIAM enzyme-specific profiles | 3.4.22.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.22.1 |
| IUBMB Enzyme Nomenclature | 3.4.22.1 |
| IntEnz | 3.4.22.1 |
| MEDLINE | Find literature relating to 3.4.22.1 |
| MetaCyc | 3.4.22.1 |
| UniProtKB/Swiss-Prot |
| P07688, CATB_BOVIN; | P43233, CATB_CHICK; | P81494, CATB_COTJA; |
| P07858, CATB_HUMAN; | Q4R5M2, CATB_MACFA; | P10605, CATB_MOUSE; |
| A1E295, CATB_PIG; | Q5R6D1, CATB_PONAB; | P00787, CATB_RAT; |
| P83205, CATB_SHEEP; | Q54QD9, CTSB_DICDI; |
|
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