| Accepted Name |
|---|
| Carboxypeptidase U.
|
| Alternative Name(s) |
|---|
| Arginine carboxypeptidase. |
| Carboxypeptidase B2. |
| Carboxypeptidase R. |
| Plasma carboxypeptidase B. |
| TAFI. |
| Thrombin-activatable fibrinolysis inhibitor. |
| Reaction catalysed |
|---|
| Release of C-terminal Arg and Lys from a polypeptide |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin
during clotting to form the unstable carboxypeptidase U.
- Activity similar to that of the more stable lysine carboxypeptidase,
except no preference is shown for Lys over Arg.
- Belongs to peptidase family M14.
|
| Cross-references |
|---|
| BRENDA | 3.4.17.20 |
| EC2PDB | 3.4.17.20 |
| PRIAM enzyme-specific profiles | 3.4.17.20 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.17.20 |
| IUBMB Enzyme Nomenclature | 3.4.17.20 |
| IntEnz | 3.4.17.20 |
| MEDLINE | Find literature relating to 3.4.17.20 |
| MetaCyc | 3.4.17.20 |
| UniProtKB/Swiss-Prot |
|
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