| Official Name |
|---|
| Dipeptidyl-peptidase IV.
|
| Alternative Name(s) |
|---|
| Dipeptidyl aminopeptidase IV. |
| DPP IV. |
| Gly-Pro naphthylamidase. |
| Post-proline dipeptidyl aminopeptidase IV. |
| Xaa-Pro-dipeptidylaminopeptidase. |
| Reaction catalysed |
|---|
| Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline |
| Comment(s) |
|---|
- A membrane-bound serine-type peptidase in mammals.
- EC 3.4.14.11 catalyzes a similar reaction.
- Belongs to peptidase family S9B.
|
| Cross-references |
|---|
| PROSITE | PDOC00587 |
| BRENDA | 3.4.14.5 |
| PUMA2 | 3.4.14.5 |
| PRIAM enzyme-specific profiles | 3.4.14.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.14.5 |
| IUBMB Enzyme Nomenclature | 3.4.14.5 |
| IntEnz | 3.4.14.5 |
| MEDLINE | Find literature relating to 3.4.14.5 |
| MetaCyc | 3.4.14.5 |
| UniProtKB/Swiss-Prot |
| P81425, DPP4_BOVIN; | Q9N2I7, DPP4_FELCA; | P27487, DPP4_HUMAN; |
| P28843, DPP4_MOUSE; | P22411, DPP4_PIG; | P14740, DPP4_RAT; |
| Q6V1X1, DPP8_HUMAN; | Q80YA7, DPP8_MOUSE; | Q86TI2, DPP9_HUMAN; |
| Q8BVG4, DPP9_MOUSE; |
|
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