| Official Name |
|---|
| Lipid-phosphate phosphatase.
|
| Alternative Name(s) |
|---|
| Dihydroxy fatty acid phosphatase. |
| Hydroxy fatty acid phosphatase. |
| Hydroxy lipid phosphatase. |
| Soluble epoxide hydrolase. |
| Reaction catalysed |
|---|
| (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O <=> (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
- The enzyme from mammals is a bifunctional enzyme: the N-terminal
domain exhibits lipid-phosphate-phosphatase activity and the
C-terminal domain has the activity of EC 3.3.2.10.
- The best substrates for this enzyme are 10-hydroxy-9-
(phosphonooxy)octadecanoates, with the threo- form being a better
substrate than the erythro- form.
- The phosphatase activity is not found in plant EC 3.3.2.10 or in
mammalian EC 3.3.2.9.
|
| Cross-references |
|---|
| BRENDA | 3.1.3.76 |
| PUMA2 | 3.1.3.76 |
| PRIAM enzyme-specific profiles | 3.1.3.76 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.3.76 |
| IUBMB Enzyme Nomenclature | 3.1.3.76 |
| IntEnz | 3.1.3.76 |
| MEDLINE | Find literature relating to 3.1.3.76 |
| MetaCyc | 3.1.3.76 |
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