ID   3.1.3.67
DE   Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase.
AN   Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase.
CA   Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol
CA   4,5-bisphosphate + phosphate.
CF   Magnesium.
CC   -!- Does not dephosphorylate inositol 4,5-bisphosphate.
CC   -!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
CC       removed, i.e., it hydrolyzes Ins(1,3,4,5)P(4) to Ins(1,4,5)P(3).
DR   P60483, PTEN_CANFA ;  P60484, PTEN_HUMAN ;  O08586, PTEN_MOUSE ;
DR   O94526, PTEN_SCHPO ;  Q9PUT6, PTEN_XENLA ;  P53916, TEP1_YEAST ;
DR   Q6XPS3, TPTE2_HUMAN;  Q4R6N0, TPTE2_MACFA;
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