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NiceZyme View of ENZYME: EC 3.1.11.2

Accepted Name
Exodeoxyribonuclease III.
Alternative Name(s)
E.coli exonuclease III.
Exonuclease III.
Reaction catalysed
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Comment(s)
  • Preference for double-stranded DNA.
  • Has endonucleolytic activity near apurinic sites on DNA.
  • Similar enzyme: Haemophilus influenzae exonuclease.
  • Formerly EC 3.1.4.27.
Cross-references
PROSITEPDOC00598
BRENDA3.1.11.2
EC2PDB3.1.11.2
PRIAM enzyme-specific profiles3.1.11.2
KEGG Ligand Database for Enzyme Nomenclature3.1.11.2
IUBMB Enzyme Nomenclature3.1.11.2
IntEnz3.1.11.2
MEDLINEFind literature relating to 3.1.11.2
MetaCyc3.1.11.2
UniProtKB/Swiss-Prot
P09030, EX3_ECOLI;  P44318, EX3_HAEIN;  P0A1B0, EX3_SALTI;  
P0A1A9, EX3_SALTY;  P37454, EXOA_BACSU;  P0A2X3, EXOA_STRPN;  
P0A2X4, EXOA_STRR6;  Q758W7, RAD17_ASHGO;  P48581, RAD17_YEAST;  
O60671, RAD1_HUMAN;  Q9QWZ1, RAD1_MOUSE;  Q5R7X9, RAD1_PONAB;  
P22193, RAD1_SCHPO;  Q99638, RAD9A_HUMAN;  Q4R5X9, RAD9A_MACFA;  
Q9Z0F6, RAD9A_MOUSE;  P14746, REC1_USTMA;  Q9BG99, TREX1_BOVIN;  
Q9NSU2, TREX1_HUMAN;  Q91XB0, TREX1_MOUSE;  Q9BQ50, TREX2_HUMAN;  
Q9R1A9, TREX2_MOUSE;  

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