| Accepted Name |
|---|
| Arylesterase.
|
| Alternative Name(s) |
|---|
| A-esterase. |
| Paraoxonase. |
| Reaction catalysed |
|---|
| A phenyl acetate + H(2)O <=> a phenol + acetate |
| Comment(s) |
|---|
- Acts on many phenolic esters.
- It is likely that the three forms of human paraoxonase are lactonases
rather than aromatic esterases.
- The natural substrates of the paraoxonases are lactones, with (+-)-5-
hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best
substrate.
|
| Cross-references |
|---|
| BRENDA | 3.1.1.2 |
| EC2PDB | 3.1.1.2 |
| PRIAM enzyme-specific profiles | 3.1.1.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.2 |
| IUBMB Enzyme Nomenclature | 3.1.1.2 |
| IntEnz | 3.1.1.2 |
| MEDLINE | Find literature relating to 3.1.1.2 |
| MetaCyc | 3.1.1.2 |
| UniProtKB/Swiss-Prot |
| P22862, ESTE_PSEFL; | Q07792, ESTE_VIBMI; | P27169, PON1_HUMAN; |
| P52430, PON1_MOUSE; | P27170, PON1_RABIT; | P55159, PON1_RAT; |
| Q58DS7, PON2_BOVIN; | P54832, PON2_CANFA; | Q90952, PON2_CHICK; |
| Q15165, PON2_HUMAN; | Q91090, PON2_MELGA; | Q62086, PON2_MOUSE; |
| Q6AXM8, PON2_RAT; |
|
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