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NiceZyme View of ENZYME: EC 2.7.7.46

Official Name
Gentamicin 2''-nucleotidyltransferase.
Alternative Name(s)
2''-aminoglycoside nucleotidyltransferase.
Reaction catalysed
Nucleoside triphosphate + gentamicin <=> diphosphate + 2''-nucleotidylgentamicin
Comment(s)
  • ATP, dATP, CTP, ITP and GTP can act as donors.
  • Kanamycin, tobramycin and sisomicin can also act as acceptors.
  • The nucleotidyl residue is transferred to the 2-hydroxy group of the 3-amino-3-deoxy-D-glucose moiety in the antibiotic.
Cross-references
BRENDA2.7.7.46
PUMA22.7.7.46
PRIAM enzyme-specific profiles2.7.7.46
KEGG Ligand Database for Enzyme Nomenclature2.7.7.46
IUBMB Enzyme Nomenclature2.7.7.46
IntEnz2.7.7.46
MEDLINEFind literature relating to 2.7.7.46
MetaCyc2.7.7.46
UniProtKB/Swiss-Prot
P0AE05, AADB1_KLEPN;  P29806, AADB2_KLEPN;  P0AE04, AADB_ECOLX;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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