ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ENZYME
Search for

NiceZyme View of ENZYME: EC 2.7.7.4

Official Name
Sulfate adenylyltransferase.
Alternative Name(s)
ATP-sulfurylase.
Sulfate adenylate transferase.
Sulfurylase.
Reaction catalysed
ATP + sulfate <=> diphosphate + adenylyl sulfate
Comment(s)
  • The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.
  • This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
Cross-references
Biochemical Pathways; map number(s)J4 ; M10 ; N10
BRENDA2.7.7.4
PUMA22.7.7.4
PRIAM enzyme-specific profiles2.7.7.4
KEGG Ligand Database for Enzyme Nomenclature2.7.7.4
IUBMB Enzyme Nomenclature2.7.7.4
IntEnz2.7.7.4
MEDLINEFind literature relating to 2.7.7.4
MetaCyc2.7.7.4
UniProtKB/Swiss-Prot
Q0A977, CYSD1_ALHEH;  Q1QWX0, CYSD1_CHRSD;  A1U3Y0, CYSD1_MARAV;  
A8FXJ5, CYSD1_SHESH;  Q0A653, CYSD2_ALHEH;  Q1QUF8, CYSD2_CHRSD;  
A1U490, CYSD2_MARAV;  A8FXM2, CYSD2_SHESH;  Q6FDA0, CYSD_ACIAD;  
A0KP36, CYSD_AERHH;  A4SRG9, CYSD_AERS4;  Q7D0L8, CYSD_AGRT5;  
A8EWR5, CYSD_ARCB4;  Q5LES4, CYSD_BACFN;  Q64VR0, CYSD_BACFR;  
Q1LTP5, CYSD_BAUCH;  A5E8X6, CYSD_BRASB;  A4YYA7, CYSD_BRASO;  
Q2YP46, CYSD_BRUA2;  Q57FI5, CYSD_BRUAB;  A9M7D7, CYSD_BRUC2;  
Q8YEX2, CYSD_BRUME;  A5VNC5, CYSD_BRUO2;  B0CJ51, CYSD_BRUSI;  
Q8G2W6, CYSD_BRUSU;  P57499, CYSD_BUCAI;  Q39EM7, CYSD_BURS3;  
Q9A881, CYSD_CAUCR;  B0T3J3, CYSD_CAUSK;  Q7NVN6, CYSD_CHRVO;  
A8ANW6, CYSD_CITK8;  Q483A0, CYSD_COLP3;  A7ZQJ6, CYSD_ECO24;  
Q8X7X4, CYSD_ECO57;  A8A3N1, CYSD_ECOHS;  A1AEU6, CYSD_ECOK1;  
Q0TEA6, CYSD_ECOL5;  Q8FEJ0, CYSD_ECOL6;  B1IUS7, CYSD_ECOLC;  
P21156, CYSD_ECOLI;  Q1R7T9, CYSD_ECOUT;  A4WDV7, CYSD_ENT38;  
A7MJ68, CYSD_ENTS8;  Q6D1A5, CYSD_ERWCT;  Q39RP7, CYSD_GEOMG;  
A5G8G3, CYSD_GEOUR;  Q2SBG0, CYSD_HAHCH;  A1WZK4, CYSD_HALHL;  
Q0C438, CYSD_HYPNA;  A6TD44, CYSD_KLEP7;  A0L6E2, CYSD_MAGSM;  
Q0ALV0, CYSD_MARMM;  A6VXC5, CYSD_MARMS;  Q11K42, CYSD_MESSB;  
Q604B7, CYSD_METCA;  B1LSA1, CYSD_METRJ;  B0U8Y5, CYSD_METS4;  
P65671, CYSD_MYCBO;  A1KI72, CYSD_MYCBP;  A5U1Y3, CYSD_MYCTA;  
P65670, CYSD_MYCTU;  Q1D9W6, CYSD_MYXXD;  Q5YUA1, CYSD_NOCFA;  
A6WVC7, CYSD_OCHA4;  Q3A3P5, CYSD_PELCD;  Q7N8L1, CYSD_PHOLL;  
Q6LM68, CYSD_PHOPR;  A4SDU0, CYSD_PROVI;  Q48ED3, CYSD_PSE14;  
Q15VB5, CYSD_PSEA6;  A6VBB6, CYSD_PSEA7;  Q02GZ8, CYSD_PSEAB;  
O50273, CYSD_PSEAE;  Q1I585, CYSD_PSEE4;  Q4KI67, CYSD_PSEF5;  
Q3ILR0, CYSD_PSEHT;  A4XQP2, CYSD_PSEMY;  A5W8T2, CYSD_PSEP1;  
Q3KHY6, CYSD_PSEPF;  B0KGN7, CYSD_PSEPG;  Q88NA9, CYSD_PSEPK;  
Q87WW0, CYSD_PSESM;  Q4ZNW4, CYSD_PSEU2;  A4VIE6, CYSD_PSEU5;  
A1ST25, CYSD_PSYIN;  Q2KB48, CYSD_RHIEC;  Q1MJV3, CYSD_RHIL3;  
Q985Q5, CYSD_RHILO;  P56892, CYSD_RHIME;  O33580, CYSD_RHITR;  
Q07UU1, CYSD_RHOP5;  Q21D94, CYSD_RHOPB;  Q2RS06, CYSD_RHORT;  
Q21IS4, CYSD_SACD2;  A9MF23, CYSD_SALAR;  Q57KI9, CYSD_SALCH;  
Q5PEH1, CYSD_SALPA;  A9N2D9, CYSD_SALPB;  P65673, CYSD_SALTI;  
P65672, CYSD_SALTY;  A8G9Y4, CYSD_SERP5;  A1S9N7, CYSD_SHEAM;  
A3D822, CYSD_SHEB5;  A6WJU3, CYSD_SHEB8;  A9L389, CYSD_SHEB9;  
Q12QM9, CYSD_SHEDO;  Q07Y91, CYSD_SHEFN;  B0TTD5, CYSD_SHEHH;  
A3QCU1, CYSD_SHELP;  Q8EB09, CYSD_SHEON;  A8H0A3, CYSD_SHEPA;  
A4Y9X3, CYSD_SHEPC;  A0KTI2, CYSD_SHESA;  Q0HFM4, CYSD_SHESM;  
Q0HYA6, CYSD_SHESR;  A1RGF7, CYSD_SHESW;  Q31XB4, CYSD_SHIBS;  
Q32CH8, CYSD_SHIDS;  Q0T1I3, CYSD_SHIF8;  P59740, CYSD_SHIFL;  
Q3YYB0, CYSD_SHISS;  Q2NVM9, CYSD_SODGM;  Q30U93, CYSD_SULDN;  
A5F579, CYSD_VIBC3;  Q9KP19, CYSD_VIBCH;  Q5E831, CYSD_VIBF1;  
A7MWG4, CYSD_VIBHB;  Q87SY0, CYSD_VIBPA;  Q8DE72, CYSD_VIBVU;  
Q7MPF3, CYSD_VIBVY;  Q3BPY6, CYSD_XANC5;  Q4UY06, CYSD_XANC8;  
B0RPG8, CYSD_XANCB;  Q8P610, CYSD_XANCP;  Q2P0H4, CYSD_XANOM;  
Q9PD79, CYSD_XYLFA;  Q87DG8, CYSD_XYLFT;  A1JJS9, CYSD_YERE8;  
A7FLY3, CYSD_YERP3;  Q1C483, CYSD_YERPA;  Q8ZBP1, CYSD_YERPE;  
Q1CLS1, CYSD_YERPN;  A4TPZ2, CYSD_YERPP;  Q66EC8, CYSD_YERPS;  
Q5NRM5, CYSD_ZYMMO;  Q10600, CYSNC_MYCTU;  O50274, CYSNC_PSEAE;  
Q7UMW2, CYSNC_RHOBA;  Q9PD78, CYSNC_XYLFA;  Q87DG7, CYSNC_XYLFT;  
A0KP35, CYSN_AERHH;  A4SRG8, CYSN_AERS4;  Q8UH69, CYSN_AGRT5;  
Q8AAP9, CYSN_BACTN;  P57498, CYSN_BUCAI;  Q7NVN5, CYSN_CHRVO;  
A8ANW5, CYSN_CITK8;  A7ZQJ5, CYSN_ECO24;  Q8X7X7, CYSN_ECO57;  
A8A3N0, CYSN_ECOHS;  A1AEU5, CYSN_ECOK1;  Q0TEA7, CYSN_ECOL5;  
Q8FEJ1, CYSN_ECOL6;  B1IUS8, CYSN_ECOLC;  P23845, CYSN_ECOLI;  
Q1R7U0, CYSN_ECOUT;  A7MJ69, CYSN_ENTS8;  Q7N8L0, CYSN_PHOLL;  
P56893, CYSN_RHIME;  O33581, CYSN_RHITR;  Q21IS6, CYSN_SACD2;  
A9MF24, CYSN_SALAR;  Q57KJ0, CYSN_SALCH;  Q5PEH2, CYSN_SALPA;  
A9N2D8, CYSN_SALPB;  Q8Z470, CYSN_SALTI;  Q8ZMF5, CYSN_SALTY;  
Q8EB10, CYSN_SHEON;  Q31XB3, CYSN_SHIBS;  Q32CH9, CYSN_SHIDS;  
Q0T1I2, CYSN_SHIF8;  Q83JX8, CYSN_SHIFL;  Q3YYB1, CYSN_SHISS;  
Q9KP20, CYSN_VIBCH;  A7MWE9, CYSN_VIBHB;  Q87SX9, CYSN_VIBPA;  
Q8DE73, CYSN_VIBVU;  Q7MPF2, CYSN_VIBVY;  Q8ZBP2, CYSN_YERPE;  
Q74ZF6, MET3_ASHGO;  A1CJC1, MET3_ASPCL;  Q4WWN8, MET3_ASPFU;  
Q8NJN1, MET3_ASPNG;  Q8NK83, MET3_ASPOR;  P56862, MET3_ASPTE;  
Q0CC19, MET3_ASPTN;  Q9Y872, MET3_CANAL;  Q6FXQ8, MET3_CANGA;  
Q2H454, MET3_CHAGB;  Q1EAF9, MET3_COCIM;  Q5KB71, MET3_CRYNE;  
Q8TG24, MET3_CRYNV;  Q6BSU5, MET3_DEBHA;  Q12555, MET3_EMENI;  
Q4I1N3, MET3_GIBZE;  Q6CNU6, MET3_KLULA;  Q8J0I4, MET3_MUCCI;  
A1D858, MET3_NEOFI;  Q7SE75, MET3_NEUCR;  Q12650, MET3_PENCH;  
Q0V6P9, MET3_PHANO;  P78937, MET3_SCHPO;  Q4P460, MET3_USTMA;  
Q6CFD2, MET3_YARLI;  P08536, MET3_YEAST;  Q9X5U0, MMCV_STRLA;  
P28603, NODP_AZOBR;  P13441, NODP_RHIME;  P72338, NODP_RHIS3;  
O07308, NODP_RHISB;  P52995, NODP_RHITR;  P28604, NODQ_AZOBR;  
P13442, NODQ_RHIME;  P72339, NODQ_RHIS3;  O07309, NODQ_RHISB;  
P52978, NODQ_RHITR;  O54820, PAPS1_CAVPO;  O43252, PAPS1_HUMAN;  
Q60967, PAPS1_MOUSE;  O95340, PAPS2_HUMAN;  O88428, PAPS2_MOUSE;  
Q27128, PAPSS_URECA;  O34764, SAT1_BACSU;  O06736, SAT2_BACSU;  
A9ENT2, SATC1_SORC5;  A9G7W0, SATC2_SORC5;  O67174, SATC_AQUAE;  
B0BZ94, SAT_ACAM1;  Q9YCR4, SAT_AERPE;  Q0VRM0, SAT_ALCBS;  
Q3MAI6, SAT_ANAVT;  O28606, SAT_ARCFU;  A7Z4H9, SAT_BACA2;  
A0RBN3, SAT_BACAH;  Q81T48, SAT_BACAN;  Q73B75, SAT_BACC1;  
A7GMW1, SAT_BACCN;  Q81FZ0, SAT_BACCR;  Q63DV8, SAT_BACCZ;  
Q6HLD3, SAT_BACHK;  Q65JT9, SAT_BACLD;  A8FD24, SAT_BACP2;  
Q5WKF4, SAT_BACSK;  Q3A8R0, SAT_CARHZ;  A0RYU6, SAT_CENSY;  
A9WFJ2, SAT_CHLAA;  Q3AQ83, SAT_CHLCH;  Q8KE30, SAT_CHLTE;  
O66036, SAT_CHRVI;  Q1IYH9, SAT_DEIGD;  P56864, SAT_DEIRA;  
A4J272, SAT_DESRM;  O76156, SAT_ENTHI;  Q5L2Y0, SAT_GEOKA;  
A4IKB5, SAT_GEOTN;  Q7NLN7, SAT_GLOVI;  A2BMW0, SAT_HYPBU;  
A8AB48, SAT_IGNH4;  Q88X61, SAT_LACPL;  B0JW81, SAT_MICAN;  
Q8EQN5, SAT_OCEIH;  A5D5R7, SAT_PELTS;  A9BFU2, SAT_PETMO;  
P84547, SAT_POPEU;  Q60FC6, SAT_PORYE;  Q4FST7, SAT_PSYA2;  
Q1QAY1, SAT_PSYCK;  A5WEH0, SAT_PSYWF;  P56863, SAT_PYRAB;  
Q54506, SAT_RIFPS;  Q1AXE5, SAT_RUBXD;  A1AVC7, SAT_RUTMC;  
Q5HL01, SAT_STAEQ;  Q8CR03, SAT_STAES;  Q4L9E7, SAT_STAHJ;  
A3DLD9, SAT_STAMF;  Q49UM4, SAT_STAS1;  Q67QB5, SAT_SYMTH;  
Q31RJ2, SAT_SYNE7;  A0LH38, SAT_SYNFM;  Q2JU97, SAT_SYNJA;  
B1XLP7, SAT_SYNP2;  Q5N2R3, SAT_SYNP6;  P74241, SAT_SYNY3;  
Q3SEZ6, SAT_THIDA;  Q111K4, SAT_TRIEI;  A5CXS6, SAT_VESOH;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ENZYME