| Accepted Name |
|---|
| [Elongation factor 2] kinase.
|
| Alternative Name(s) |
|---|
| Ca/CaM-kinase III. |
| Calmodulin-dependent protein kinase III. |
| CaM kinase III. |
| EEF2 kinase. |
| EEF2K. |
| EF2K. |
| Reaction catalysed |
|---|
| ATP + [elongation factor 2] <=> ADP + [elongation factor 2] phosphate |
| Cofactor(s) |
|---|
| Calcium.
|
| Comment(s) |
|---|
- Requires calmodulin for activity.
- Can also be phosphorylated by the catalytic subunit of EC 2.7.11.11.
- Elongation factor 2 is phosphorylated in several cell types in
response to various growth factors, hormones and other stimuli that
raise intracellular Ca(2+).
|
| Cross-references |
|---|
| PROSITE | PDOC51158 |
| BRENDA | 2.7.11.20 |
| EC2PDB | 2.7.11.20 |
| PRIAM enzyme-specific profiles | 2.7.11.20 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.20 |
| IUBMB Enzyme Nomenclature | 2.7.11.20 |
| IntEnz | 2.7.11.20 |
| MEDLINE | Find literature relating to 2.7.11.20 |
| MetaCyc | 2.7.11.20 |
| UniProtKB/Swiss-Prot |
|
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