| Accepted Name |
|---|
| [Beta-adrenergic-receptor] kinase.
|
| Alternative Name(s) |
|---|
| ADRBK1. |
| Adrenergic receptor kinase. |
| BARK1. |
| Beta(2)ARK. |
| Beta-adrenergic receptor-specific kinase. |
| Beta-adrenergic-receptor kinase. |
| Beta-adrenergic-receptor kinase (phosphorylating). |
| Beta-adrenoceptor kinase. |
| Beta-AR kinase. |
| Beta-ARK. |
| Beta-receptor kinase. |
| Reaction catalysed |
|---|
| ATP + [beta-adrenergic receptor] <=> ADP + [beta-adrenergic receptor] phosphate |
| Comment(s) |
|---|
- Acts on the agonist-occupied form of the receptor; also
phosphorylates rhodopsin, but more slowly.
- Does not act on casein or histones.
- Inhibited by Zn(2+) and digitonin but is unaffected by cyclic-AMP
(cf. EC 2.7.11.14 and EC 2.7.11.16).
- Formerly EC 2.7.1.126.
|
| Cross-references |
|---|
| PROSITE | PDOC00100 |
| BRENDA | 2.7.11.15 |
| EC2PDB | 2.7.11.15 |
| PRIAM enzyme-specific profiles | 2.7.11.15 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.15 |
| IUBMB Enzyme Nomenclature | 2.7.11.15 |
| IntEnz | 2.7.11.15 |
| MEDLINE | Find literature relating to 2.7.11.15 |
| MetaCyc | 2.7.11.15 |
| UniProtKB/Swiss-Prot |
| P21146, ARBK1_BOVIN; | O97627, ARBK1_DIDMA; | P25098, ARBK1_HUMAN; |
| Q64682, ARBK1_MESAU; | Q99MK8, ARBK1_MOUSE; | P26817, ARBK1_RAT; |
| P26818, ARBK2_BOVIN; | P35626, ARBK2_HUMAN; | Q3UYH7, ARBK2_MOUSE; |
| P26819, ARBK2_RAT; |
|
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