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NiceZyme View of ENZYME: EC 2.7.11.14

Accepted Name
Rhodopsin kinase.
Alternative Name(s)
Cone opsin kinase.
G-protein-coupled receptor kinase 1.
GPCR kinase 1.
Opsin kinase.
Opsin kinase (phosphorylating).
Rhodopsin kinase (phosphorylating).
RK.
Reaction catalysed
ATP + [rhodopsin] <=> ADP + [rhodopsin] phosphate
Comment(s)
  • Acts on the bleached or activated form of rhodopsin.
  • Also phosphorylates the beta-adrenergic receptor, but more slowly.
  • Does not act on casein, histones or phosphovitin.
  • Inhibited by Zn(2+) and digitonin (cf. EC 2.7.11.15 and EC 2.7.11.16).
  • Formerly EC 2.7.1.125.
Cross-references
PROSITEPDOC00100
BRENDA2.7.11.14
EC2PDB2.7.11.14
PRIAM enzyme-specific profiles2.7.11.14
KEGG Ligand Database for Enzyme Nomenclature2.7.11.14
IUBMB Enzyme Nomenclature2.7.11.14
IntEnz2.7.11.14
MEDLINEFind literature relating to 2.7.11.14
MetaCyc2.7.11.14
UniProtKB/Swiss-Prot
P28327, RK_BOVIN;  Q15835, RK_HUMAN;  Q9WVL4, RK_MOUSE;  
Q63651, RK_RAT;  

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