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NiceZyme View of ENZYME: EC 2.5.1.18

Official Name
Glutathione transferase.
Alternative Name(s)
Glutathione S-alkyltransferase.
Glutathione S-aralkyltransferase.
Glutathione S-aryltransferase.
S-(hydroxyalkyl)glutathione lyase.
Reaction catalysed
RX + glutathione <=> HX + R-S-glutathione
Comment(s)
  • A group of enzymes of broad specificity.
  • R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
  • Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
  • Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
Cross-references
Biochemical Pathways; map number(s)H7
BRENDA2.5.1.18
PUMA22.5.1.18
PRIAM enzyme-specific profiles2.5.1.18
KEGG Ligand Database for Enzyme Nomenclature2.5.1.18
IUBMB Enzyme Nomenclature2.5.1.18
IntEnz2.5.1.18
MEDLINEFind literature relating to 2.5.1.18
MetaCyc2.5.1.18

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