| Official Name |
|---|
| Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase.
|
| Alternative Name(s) |
|---|
| GalT. |
| Glycoprotein 4-beta-galactosyltransferase. |
| Thyroid galactosyltransferase. |
| UDP-galactose--glycoprotein galactosyltransferase. |
| Reaction catalysed |
|---|
| UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide <=> UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide |
| Comment(s) |
|---|
- Terminal N-acetyl-beta-D-glucosaminyl residues in polysaccharides,
glycoproteins and glycopeptides can act as acceptor.
- High activity is shown toward such residues in branched-chain
polysaccharides when these are linked by beta-1,6 links to galactose
residues; lower activity toward residues linked to galactose by beta-
1,3 links.
- A component of EC 2.4.1.22.
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | R3 |
| BRENDA | 2.4.1.38 |
| PUMA2 | 2.4.1.38 |
| PRIAM enzyme-specific profiles | 2.4.1.38 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.38 |
| IUBMB Enzyme Nomenclature | 2.4.1.38 |
| IntEnz | 2.4.1.38 |
| MEDLINE | Find literature relating to 2.4.1.38 |
| MetaCyc | 2.4.1.38 |
| UniProtKB/Swiss-Prot |
| P08037, B4GT1_BOVIN; | P15291, B4GT1_HUMAN; | P15535, B4GT1_MOUSE; |
| P80225, B4GT1_RAT; | Q80WN9, B4GT2_CRIGR; | O60909, B4GT2_HUMAN; |
| Q9Z2Y2, B4GT2_MOUSE; | Q5EA87, B4GT3_BOVIN; | Q80WN8, B4GT3_CRIGR; |
| O60512, B4GT3_HUMAN; | Q91YY2, B4GT3_MOUSE; | Q5NVN3, B4GT3_PONAB; |
| Q6P768, B4GT3_RAT; |
|
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