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ENZYME

ENZYME entry: EC 2.4.1.274

Accepted Name
glucosylceramide beta-1,4-galactosyltransferase
Alternative Name(s)
lactosylceramide synthase
Reaction catalysed
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose <=> a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP
Comment(s)
Involved in the synthesis of several different major classes of glycosphingolipids.
Cross-references
BRENDA2.4.1.274
EC2PDB2.4.1.274
ExplorEnz2.4.1.274
PRIAM enzyme-specific profiles2.4.1.274
KEGG Ligand Database for Enzyme Nomenclature2.4.1.274
IUBMB Enzyme Nomenclature2.4.1.274
IntEnz2.4.1.274
MEDLINEFind literature relating to 2.4.1.274
MetaCyc2.4.1.274
Rhea expert-curated reactions2.4.1.274
UniProtKB/Swiss-Prot
Q3YL68, B4GT5_DANREO43286, B4GT5_HUMANQ9JMK0, B4GT5_MOUSE
A0A1S6M251, B4GT5_PIGQ9UBX8, B4GT6_HUMANQ9WVK5, B4GT6_MOUSE
O88419, B4GT6_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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