| Accepted Name |
|---|
| Glutaminyl-peptide cyclotransferase.
|
| Alternative Name(s) |
|---|
| Glutaminyl cyclase. |
| Glutaminyl-tRNA cyclotransferase. |
| Reaction catalysed |
|---|
| L-glutaminyl-peptide <=> 5-oxoprolyl-peptide + NH(3) |
| Comment(s) |
|---|
- Involved in the formation of thyrotropin-releasing hormone and other
biologically active peptides containing N-terminal pyroglutamyl
residues.
- The enzyme from papaya also acts on glutaminyl-tRNA.
|
| Cross-references |
|---|
| BRENDA | 2.3.2.5 |
| EC2PDB | 2.3.2.5 |
| PRIAM enzyme-specific profiles | 2.3.2.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.2.5 |
| IUBMB Enzyme Nomenclature | 2.3.2.5 |
| IntEnz | 2.3.2.5 |
| MEDLINE | Find literature relating to 2.3.2.5 |
| MetaCyc | 2.3.2.5 |
| UniProtKB/Swiss-Prot |
|
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