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NiceZyme View of ENZYME: EC 2.1.1.34

Official Name
tRNA guanosine-2'-O-methyltransferase.
Alternative Name(s)
S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase.
Transfer ribonucleate guanosine 2'-methyltransferase.
tRNA (Gm18) 2'-O-methyltransferase.
tRNA (Gm18) methyltransferase.
tRNA (guanosine 2')-methyltransferase.
tRNA (guanosine-2'-O-)-methyltransferase.
tRNA guanosine 2'-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine
Comment(s)
  • Methylates the 2'-hydroxy group of a guanosine present in a GG sequence at position 18.
  • Yeast tRNA(Phe) is one of the best substrate tRNAs.
Cross-references
BRENDA2.1.1.34
PUMA22.1.1.34
PRIAM enzyme-specific profiles2.1.1.34
KEGG Ligand Database for Enzyme Nomenclature2.1.1.34
IUBMB Enzyme Nomenclature2.1.1.34
IntEnz2.1.1.34
MEDLINEFind literature relating to 2.1.1.34
MetaCyc2.1.1.34
UniProtKB/Swiss-Prot
Q07527, TRM3_YEAST;  O67577, TRMH_AQUAE;  P0AGJ3, TRMH_ECO57;  
P0AGJ2, TRMH_ECOLI;  P0AGJ4, TRMH_SHIFL;  

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