| Official Name |
|---|
| tRNA (guanine-N(2)-)-methyltransferase.
|
| Alternative Name(s) |
|---|
| N(2),N(2)-dimethylguanine tRNA methyltransferase. |
| tRNA 2,2-dimethylguanosine-26 methyltransferase. |
| tRNA(guanine-26,N(2)-N(2)) methyltransferase. |
| tRNA(m(2,2)G26)dimethyltransferase. |
| Reaction catalysed |
|---|
| S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing N(2)-methylguanine |
| Comment(s) |
|---|
| In eukaryotic tRNAs, two N(2)-guanine methylations occur, at the
N(2)-methylguanine at position 10 and the N(2)-methylguanine at
position 29.
|
| Cross-references |
|---|
| BRENDA | 2.1.1.32 |
| PUMA2 | 2.1.1.32 |
| PRIAM enzyme-specific profiles | 2.1.1.32 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.32 |
| IUBMB Enzyme Nomenclature | 2.1.1.32 |
| IntEnz | 2.1.1.32 |
| MEDLINE | Find literature relating to 2.1.1.32 |
| MetaCyc | 2.1.1.32 |
| UniProtKB/Swiss-Prot |
| Q9YDY7, TRM1_AERPE; | O67010, TRM1_AQUAE; | Q9LFU5, TRM1_ARATH; |
| O29443, TRM1_ARCFU; | Q23270, TRM1_CAEEL; | Q9VK89, TRM1_DROME; |
| Q5UYV8, TRM1_HALMA; | P57705, TRM1_HALSA; | Q18EA0, TRM1_HALWD; |
| Q9NXH9, TRM1_HUMAN; | Q8TGX6, TRM1_METAC; | Q466T6, TRM1_METBF; |
| Q12Y46, TRM1_METBU; | Q58356, TRM1_METJA; | Q8PU28, TRM1_METMA; |
| Q9HH73, TRM1_METMP; | A5UM08, TRM1_METS3; | Q2NI56, TRM1_METST; |
| O27258, TRM1_METTH; | Q3TX08, TRM1_MOUSE; | Q3IUJ2, TRM1_NATPD; |
| Q9V1P3, TRM1_PYRAB; | Q8ZWT5, TRM1_PYRAE; | P81554, TRM1_PYRFU; |
| O59493, TRM1_PYRHO; | Q5JIB3, TRM1_PYRKO; | P20300, TRM1_PYRWO; |
| Q9P804, TRM1_SCHPO; | Q97ZH0, TRM1_SULSO; | Q971V9, TRM1_SULTO; |
| P57706, TRM1_THEAC; | Q97AR2, TRM1_THEVO; | P15565, TRM1_YEAST; |
| Q9SRU7, TRM2_ARATH; |
|
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