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ENZYME

ENZYME entry: EC 2.1.1.159

Accepted Name
theobromine synthase
Alternative Name(s)
monomethylxanthine methyltransferase
MXMT
Reaction catalysed
7-methylxanthine + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + theobromine
Comment(s)
  • Can also catalyze the conversion of paraxanthine into caffeine, although the paraxanthine pathway is considered to be a minor pathway for caffeine biosynthesis.
  • This is the third enzyme in the caffeine biosynthesis pathway.
Cross-references
BRENDA2.1.1.159
EC2PDB2.1.1.159
ExplorEnz2.1.1.159
PRIAM enzyme-specific profiles2.1.1.159
KEGG Ligand Database for Enzyme Nomenclature2.1.1.159
IUBMB Enzyme Nomenclature2.1.1.159
IntEnz2.1.1.159
MEDLINEFind literature relating to 2.1.1.159
MetaCyc2.1.1.159
Rhea expert-curated reactions2.1.1.159
UniProtKB/Swiss-Prot
A0A061FMF5, BTS1_THECCA0A061FKL9, BTS2_THECCA0A061FTC2, BTS3_THECC
A0A061FLA2, BTS4_THECCA0A061FKM4, BTS5_THECCA0A6C0WX00, CKTBS_CAMSB
Q2HXL9, ICS1_CAMIRQ9AVJ9, MXMT1_COFARQ4U5S1, MXMT1_COFCA
Q84PP7, MXMT2_COFARQ8RVM0, MXMT2_COFCAQ2HXI6, PCS1_CAMPL
Q2HXI5, PCS2_CAMPL

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