| Official Name |
| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.
|
| Alternative Name(s) |
| Cobalamin-independent methionine synthase. |
| Homocysteine methylase. |
| Methionine synthase (cobalamin-independent). |
| Methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase. |
| Tetrahydropteroylglutamate-homocysteine transmethylase. |
| Reaction catalysed |
| 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine <=> tetrahydropteroyltri-L-glutamate + L-methionine |
| Cofactor(s) |
| Zinc.
|
| Comment(s) |
- Requires phosphate.
- The enzyme from Escherichia coli also requires a reducing system.
- Unlike EC 2.1.1.13 this enzyme does not contain cobalamin.
|
| Cross-references |
| Biochemical Pathways; map number(s) | H3 |
| BRENDA | 2.1.1.14 |
| PUMA2 | 2.1.1.14 |
| PRIAM enzyme-specific profiles | 2.1.1.14 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.14 |
| IUBMB Enzyme Nomenclature | 2.1.1.14 |
| IntEnz | 2.1.1.14 |
| MEDLINE | Find literature relating to 2.1.1.14 |
| MetaCyc | 2.1.1.14 |