| Official Name |
|---|
| 2-furoyl-CoA dehydrogenase.
|
| Alternative Name(s) |
|---|
| Furoyl-CoA hydroxylase. |
| Reaction catalysed |
|---|
| 2-furoyl-CoA + H(2)O + acceptor <=> S-(5-hydroxy-2-furoyl)-CoA + reduced acceptor |
| Cofactor(s) |
|---|
| Copper.
|
| Comment(s) |
|---|
- The oxygen atom of the -OH produced is derived from water, not O(2).
- The actual oxidative step is probably dehydrogenation of a hydrated
form -CHOH-CH(2)- to -C(OH)=CH-, which tautomerizes non-enzymically
to -CO-CH(2)-, giving (5-oxo-4,5-dihydro-2-furoyl)-CoA.
- Methylene blue, nitro blue tetrazolium and a membrane fraction from
Pseudomonas putida can act as acceptors.
|
| Cross-references |
|---|
| BRENDA | 1.3.99.8 |
| PUMA2 | 1.3.99.8 |
| PRIAM enzyme-specific profiles | 1.3.99.8 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.99.8 |
| IUBMB Enzyme Nomenclature | 1.3.99.8 |
| IntEnz | 1.3.99.8 |
| MEDLINE | Find literature relating to 1.3.99.8 |
| MetaCyc | 1.3.99.8 |
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