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NiceZyme View of ENZYME: EC 1.2.1.72

Official Name
Erythrose-4-phosphate dehydrogenase.
Alternative Name(s)
E4P dehydrogenase.
E4PDH.
Erythrose 4-phosphate dehydrogenase.
Reaction catalysed
D-erythrose 4-phosphate + NAD(+) + H(2)O <=> 4-phosphoerythronate + NADH
Comment(s)
  • Was originally thought to be an EC 1.2.1.12, but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate.
  • Forms part of the pyridoxal-5'-phosphate coenzyme biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
Cross-references
PROSITEPDOC00069
BRENDA1.2.1.72
PUMA21.2.1.72
PRIAM enzyme-specific profiles1.2.1.72
KEGG Ligand Database for Enzyme Nomenclature1.2.1.72
IUBMB Enzyme Nomenclature1.2.1.72
IntEnz1.2.1.72
MEDLINEFind literature relating to 1.2.1.72
MetaCyc1.2.1.72
UniProtKB/Swiss-Prot
A0KGD2, E4PD_AERHH;  A4SRF2, E4PD_AERS4;  A8APE1, E4PD_CITK8;  
Q47XD5, E4PD_COLP3;  A7ZR35, E4PD_ECO24;  P0A9B8, E4PD_ECO57;  
A8A467, E4PD_ECOHS;  A1AFB1, E4PD_ECOK1;  Q0TDS9, E4PD_ECOL5;  
P0A9B7, E4PD_ECOL6;  B1IT76, E4PD_ECOLC;  P0A9B6, E4PD_ECOLI;  
Q1R7A6, E4PD_ECOUT;  A4WE72, E4PD_ENT38;  A7MJQ2, E4PD_ENTS8;  
Q6D086, E4PD_ERWCT;  Q5QVL6, E4PD_IDILO;  A6TDT2, E4PD_KLEP7;  
Q7N7Z6, E4PD_PHOLL;  Q6LMN0, E4PD_PHOPR;  Q15QK3, E4PD_PSEA6;  
Q3ILL8, E4PD_PSEHT;  A1SVN9, E4PD_PSYIN;  A9MRF0, E4PD_SALAR;  
Q57K44, E4PD_SALCH;  Q5PJI5, E4PD_SALPA;  A9N3Q6, E4PD_SALPB;  
Q8XGA4, E4PD_SALTI;  Q7CPU5, E4PD_SALTY;  A1S9A4, E4PD_SHEAM;  
Q12QA4, E4PD_SHEDO;  Q087Q7, E4PD_SHEFN;  B0TUC0, E4PD_SHEHH;  
A3QAX7, E4PD_SHELP;  Q8EIB2, E4PD_SHEON;  A8H0M9, E4PD_SHEPA;  
A4Y3R9, E4PD_SHEPC;  A0L0K7, E4PD_SHESA;  Q0HM63, E4PD_SHESM;  
Q0HRM3, E4PD_SHESR;  A1RN69, E4PD_SHESW;  Q31WI6, E4PD_SHIBS;  
Q32BY7, E4PD_SHIDS;  Q0T0X3, E4PD_SHIF8;  P0A9B9, E4PD_SHIFL;  
Q3YXU5, E4PD_SHISS;  A5F9G1, E4PD_VIBC3;  P0C6C2, E4PD_VIBCH;  
Q5E7R0, E4PD_VIBF1;  A7MTQ2, E4PD_VIBHB;  Q87LL0, E4PD_VIBPA;  
Q8DCA1, E4PD_VIBVU;  Q7MHL0, E4PD_VIBVY;  A1JPR1, E4PD_YERE8;  
Q1CB62, E4PD_YERPA;  Q7CGS4, E4PD_YERPE;  Q1CEY2, E4PD_YERPN;  
Q666Q0, E4PD_YERPS;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-

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