| Accepted Name |
|---|
| Acetaldehyde dehydrogenase (acetylating).
|
| Alternative Name(s) |
|---|
| Acylating acetaldehyde dehydrogenase. |
| Aldehyde dehydrogenase (acylating). |
| Reaction catalysed |
|---|
| Acetaldehyde + CoA + NAD(+) <=> acetyl-CoA + NADH |
| Comment(s) |
|---|
- Also acts, more slowly, on glycolaldehyde, propanal and butanal.
- In Pseudomonas species, this enzyme forms part of a bifunctional
enzyme with EC 4.1.3.39.
- It is the final enzyme in the meta-cleavage pathway for the
degradation of phenols, cresols and catechol, converting the
acetaldehyde produced by EC 4.1.3.39 into acetyl-CoA.
- NADP(+) can replace NAD(+) but the rate of reaction is much slower.
|
| Cross-references |
|---|
| PROSITE | PDOC00059 |
| BRENDA | 1.2.1.10 |
| EC2PDB | 1.2.1.10 |
| PRIAM enzyme-specific profiles | 1.2.1.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.1.10 |
| IUBMB Enzyme Nomenclature | 1.2.1.10 |
| IntEnz | 1.2.1.10 |
| MEDLINE | Find literature relating to 1.2.1.10 |
| MetaCyc | 1.2.1.10 |
| UniProtKB/Swiss-Prot |
| Q24803, ADH2_ENTHI; | P33744, ADHE_CLOAB; | P0A9Q8, ADHE_ECO57; |
| P0A9Q7, ADHE_ECOLI; | A4JPX8, MHPF_BURVG; | Q13QH7, MHPF_BURXL; |
| Q47B12, MHPF_DECAR; | A7ZI98, MHPF_ECO24; | Q8X5J9, MHPF_ECO57; |
| A7ZWZ8, MHPF_ECOHS; | P77580, MHPF_ECOLI; | A6TAC5, MHPF_KLEP7; |
| Q49KG0, MHPF_PSEPU; | Q46NW7, MHPF_RALEJ; | Q3Z555, MHPF_SHISS; |
|
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