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NiceZyme View of ENZYME: EC 1.14.19.6

Accepted Name
Delta(12)-fatty-acid desaturase.
Alternative Name(s)
Delta(12) desaturase.
Delta(12) fatty acid desaturase.
Delta(12)(omega-6)-desaturase.
Delta(12)-desaturase.
Oleoyl-CoA Delta(12) desaturase.
Reaction catalysed
Acyl-CoA + reduced acceptor + O(2) <=> Delta(12)-acyl-CoA + acceptor + 2 H(2)O
Comment(s)
  • In the yeast Lipomyces starkeyi and in the American cockroach Periplaneta americana, this microsomal enzyme converts oleoyl-CoA into linoleoyl-CoA.
  • In the moths Cadra cautella and Spodoptera, the enzyme converts (Z)-9-tetradecenoic acid into (9Z,12E)-tetradeca-9,12-dienoic acid, which is reduced and acetylated to form the acetate ester pheromone.
Cross-references
BRENDA1.14.19.6
EC2PDB1.14.19.6
PRIAM enzyme-specific profiles1.14.19.6
KEGG Ligand Database for Enzyme Nomenclature1.14.19.6
IUBMB Enzyme Nomenclature1.14.19.6
IntEnz1.14.19.6
MEDLINEFind literature relating to 1.14.19.6
MetaCyc1.14.19.6

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-