| Official Name |
| Flavonoid 3',5'-hydroxylase.
|
| Alternative Name(s) |
| F3',5'H. |
| F3'5'H. |
| Reaction catalysed |
|
| Cofactor(s) |
| Heme-thiolate.
|
| Comment(s) |
- The 3',5'-dihydroxyflavanone is formed via the 3'-hydroxyflavanone.
- In Petunia hybrida the enzyme acts on naringenin, eriodictyol,
dihydroquercetin (taxifolin) and dihydrokaempferol (aromadendrin).
- The enzyme catalyzes the hydroxylation of 5,7,4'-trihydroxyflavanone
(naringenin) at either the 3' position to form eriodictyol or at both
the 3' and 5' positions to form 5,7,3',4',5'-pentahydroxyflavanone
(dihydrotricetin).
- The enzyme also catalyzes the hydroxylation of
3,5,7,3',4'-pentahydroxyflavanone (taxifolin) at the 5' position,
forming ampelopsin.
- NADH is not a good substitute for NADPH.
|
| Cross-references |
| PROSITE | PDOC00081 |
| BRENDA | 1.14.13.88 |
| PUMA2 | 1.14.13.88 |
| PRIAM enzyme-specific profiles | 1.14.13.88 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.88 |
| IUBMB Enzyme Nomenclature | 1.14.13.88 |
| IntEnz | 1.14.13.88 |
| MEDLINE | Find literature relating to 1.14.13.88 |
| MetaCyc | 1.14.13.88 |
| UniProtKB/Swiss-Prot |
|