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ENZYME

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NiceZyme View of ENZYME: EC 1.14.13.78

Official Name

Ent-kaurene oxidase.

Reaction catalysed

Ent-kaur-16-ene + NADPH + O(2) <=> ent-kaur-16-en-19-ol + NADP(+) + H(2)O
Ent-kaur-16-en-19-ol + NADPH + O(2) <=> ent-kaur-16-en-19-al + NADP(+) + 2 H(2)O
Ent-kaur-16-en-19-al + NADPH + O(2) <=> ent-kaur-16-en-19-oate + NADP(+) + H(2)O

Comment(s)

Requires cytochrome P450.
Catalyzes three sucessive oxidations of the 4-methyl group of ent- kaurene giving kaurenoic acid.

Cross-references

PROSITE

BRENDA

PUMA2

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature

IntEnz

MEDLINE

MetaCyc

UniProtKB/Swiss-Prot

Q93ZB2, KO1_ARATH;

O94142, KO1_GIBFU;