NiceZyme View of ENZYME: EC 1.14.13.76
| Accepted Name | ||
|---|---|---|
| Taxane 10-beta-hydroxylase. | ||
| Alternative Name(s) | ||
| 5-alpha-taxadienol-10-beta-hydroxylase. | ||
| Reaction catalysed | ||
| Taxa-4(20),11-dien-5-alpha-yl acetate + NADPH + O(2) <=> 10-beta-hydroxytaxa-4(20),11-dien-5-alpha-yl acetate + NADP(+) + H(2)O | ||
| Cofactor(s) | ||
| Heme-thiolate. | ||
| Comment(s) | ||
| Involved in the biosynthesis of the diterpenoid antineoplastic drug taxol (paclitaxel). | ||
| Cross-references | ||
| PROSITE | PDOC00081 | |
| BRENDA | 1.14.13.76 | |
| EC2PDB | 1.14.13.76 | |
| PRIAM enzyme-specific profiles | 1.14.13.76 | |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.76 | |
| IUBMB Enzyme Nomenclature | 1.14.13.76 | |
| IntEnz | 1.14.13.76 | |
| MEDLINE | Find literature relating to 1.14.13.76 | |
| MetaCyc | 1.14.13.76 | |
| UniProtKB/Swiss-Prot |
| |
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