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NiceZyme View of ENZYME: EC 1.14.13.72

Official Name
Methylsterol monooxygenase.
Alternative Name(s)
4-methylsterol oxidase.
Methylsterol hydroxylase.
Reaction catalysed
  • 4,4-dimethyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) <=> 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)(+) + H(2)O
  • 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) <=> 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)(+) + 2 H(2)O
  • 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)H + O(2) <=> 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate + NAD(P)(+) + H(2)O
Comment(s)
  • Requires cytochrome b5.
  • Also acts on 4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol.
  • The sterol can be based on cycloartenol as well as lanosterol.
  • Formerly EC 1.14.99.16.
Cross-references
BRENDA1.14.13.72
PUMA21.14.13.72
PRIAM enzyme-specific profiles1.14.13.72
KEGG Ligand Database for Enzyme Nomenclature1.14.13.72
IUBMB Enzyme Nomenclature1.14.13.72
IntEnz1.14.13.72
MEDLINEFind literature relating to 1.14.13.72
MetaCyc1.14.13.72

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