| Official Name |
|---|
| Alkene monooxygenase.
|
| Alternative Name(s) |
|---|
| Alkene epoxygenase. |
| Reaction catalysed |
|---|
| Propene + NADH + O(2) <=> 1,2-epoxypropane + NAD(+) + H(2)O |
| Cofactor(s) |
|---|
| Iron.
|
| Comment(s) |
|---|
- The enzyme from Xanthobacter sp. strain Py2 is a multicomponent
enzyme comprising:
(1) an NADH reductase, which provides the reductant for O(2)
activation.
(2) a Rieske-type ferredoxin, which is an electron-transfer protein.
(3) an oxygenase, which contains the catalytic center for alkene
epoxidation.
(4) a small protein of unknown function that is essential for
activity.
- The enzyme oxygenates C(2) to C(6) aliphatic alkenes.
- With 1,2-epoxypropane as substrate, the stereospecificity of the
epoxypropane formed is 95% (R) and 5% (S).
|
| Cross-references |
|---|
| BRENDA | 1.14.13.69 |
| PUMA2 | 1.14.13.69 |
| PRIAM enzyme-specific profiles | 1.14.13.69 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.69 |
| IUBMB Enzyme Nomenclature | 1.14.13.69 |
| IntEnz | 1.14.13.69 |
| MEDLINE | Find literature relating to 1.14.13.69 |
| MetaCyc | 1.14.13.69 |
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