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NiceZyme View of ENZYME: EC 1.1.1.49

Official Name
Glucose-6-phosphate dehydrogenase.
Alternative Name(s)
G6PD.
G6PDH.
Glucose-6-phosphate 1-dehydrogenase.
GPD.
Reaction catalysed
D-glucose 6-phosphate + NADP(+) <=> D-glucono-1,5-lactone 6-phosphate + NADPH
Comment(s)
  • Also acts slowly on beta-D-glucose and other sugars.
  • Certain preparations reduce NAD(+) as well as NADP(+).
Cross-references
Biochemical Pathways; map number(s)C5
PROSITEPDOC00067
BRENDA1.1.1.49
PUMA21.1.1.49
PRIAM enzyme-specific profiles1.1.1.49
KEGG Ligand Database for Enzyme Nomenclature1.1.1.49
IUBMB Enzyme Nomenclature1.1.1.49
IntEnz1.1.1.49
MEDLINEFind literature relating to 1.1.1.49
MetaCyc1.1.1.49
UniProtKB/Swiss-Prot
Q43727, G6PD1_ARATH;  Q00612, G6PD1_MOUSE;  Q9FY99, G6PD2_ARATH;  
P97324, G6PD2_MOUSE;  P0A587, G6PD2_MYCBO;  P0A586, G6PD2_MYCTU;  
O59812, G6PD2_SCHPO;  Q8L743, G6PD3_ARATH;  O14137, G6PD3_SCHPO;  
Q93ZW0, G6PD4_ARATH;  Q9LK23, G6PD5_ARATH;  Q9FJI5, G6PD6_ARATH;  
Q43839, G6PDC_SOLTU;  O24357, G6PDC_SPIOL;  Q43793, G6PDC_TOBAC;  
P77809, G6PD_ACTAC;  P48992, G6PD_ANASP;  P48826, G6PD_ASPNG;  
P54547, G6PD_BACSU;  O51581, G6PD_BORBU;  Q7YS37, G6PD_BOSIN;  
P57405, G6PD_BUCAI;  Q8K9M2, G6PD_BUCAP;  Q89AI7, G6PD_BUCBP;  
Q27464, G6PD_CAEEL;  P41571, G6PD_CERCA;  Q9PKK8, G6PD_CHLMU;  
Q9Z8U6, G6PD_CHLPN;  O84188, G6PD_CHLTR;  O55044, G6PD_CRIGR;  
Q23711, G6PD_CULPI;  P37986, G6PD_DICD3;  Q557D2, G6PD_DICDI;  
P15588, G6PD_DIDMA;  P12646, G6PD_DROME;  Q24625, G6PD_DROSI;  
Q27638, G6PD_DROYA;  Q8XCJ6, G6PD_ECO57;  P0AC54, G6PD_ECOL6;  
P0AC53, G6PD_ECOLI;  P41764, G6PD_EMENI;  P54996, G6PD_FUGRU;  
P44311, G6PD_HAEIN;  Q9ZKB2, G6PD_HELPJ;  P56110, G6PD_HELPY;  
P11413, G6PD_HUMAN;  Q25019, G6PD_HYACE;  P48828, G6PD_KLULA;  
P11411, G6PD_LEUME;  Q29492, G6PD_MACRO;  P80619, G6PD_MAIZE;  
Q42919, G6PD_MEDSA;  P0A585, G6PD_MYCBO;  P0A584, G6PD_MYCTU;  
P48848, G6PD_NOSPU;  P11410, G6PD_PICJA;  O68282, G6PD_PSEAE;  
P05370, G6PD_RAT;  Q9Z3S2, G6PD_RHIME;  Q25537, G6PD_SARBU;  
O00091, G6PD_SCHPO;  P37830, G6PD_SOLTU;  O54537, G6PD_STRPN;  
P29686, G6PD_SYNP7;  P73411, G6PD_SYNY3;  Q9X0N9, G6PD_THEMA;  
O83491, G6PD_TREPA;  P11412, G6PD_YEAST;  P21907, G6PD_ZYMMO;  

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